N-alkyl-pyrrolidones

N-Alkyl-pyrrolidones are extensively used solvents. In Europe they are produced and imported in the margin of multiple thousand tonnes. They play an important role in the production of polymers, paints and cleaning products. The most common pyrolidones N-Methyl-2-pyrrolidone und N-Ethyl-2-pyrrolidone are classified as reproductive toxicants.

Sub-groups

• N-Methyl-2-pyrrolidone

  A versatile solvent classified as reproductive toxicant
• N-Ethyl-2-pyrrolidone

  A versatile solvent classified as reproductive toxicant. Substitute of N-Methyl-2-pyrrolidone (NMP)

Specimen

• Students

  Student groups with an even number of female and male students at the age of 20 to 29.

  Search data

Sampling area

Sampling period

Extended information

Literature

• Metabolites of the alkyl pyrrolidone solvents NMP and NEP in 24-h urine samples of the German Environmental Specimen Bank from 1991 to 2014
  Ulrich, Nadin; Bury, Daniel; Koch, Holger M.; Rüther, Maria; Weber, Till; Käfferlein, Heiko-Udo; Weiss, Tobias; Brüning, Thomas; Kolossa-Gehring, Marike
  Int Arch Occup Environ Health (2018); online 22 August 2018, 2018