Di(2-propylheptyl)phthalate (DPHP)
DPHP; phthalic acid bis(2-propylheptyl) ester; formula: C28H46O4; CAS Registry Number: 53306-54-0
Analytically difficult to grasp
Di-(2-propylheptyl)phthalate (DPHP) is used as plasticizer, especially in polymers like PVC. Due to analytical difficulties within a total phthalate determination, DPHP is analysed with a specific method.
The Environmental Specimen Bank do not analyses the parent substance DPHP in human samples, but its main metabolites.
Substances
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cx-MPHxPMono(propyl-6-carboxyhexyl) phthalate is a secondary metabolite of DPHP.
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OH-MPHPMono(propyl-6-hydroxyheptyl) phthalate is a secondary metabolite of DPHP.
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Oxo-MPHPMono(propyl-6-oxo-heptyl) phthalate is a secondary metabolite of DPHP.
Specimen
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Student groups with an even number of female and male students at the age of 20 to 29.
Sampling area
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4 university cities as sampling areas.
Sampling period
1999 - 2017
Extended information
Literature
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Bis-(2-propylheptyl)phthalate (DPHP) metabolites emerging in 24 hour urine samples from the German Environmental Specimen Bank (1999 to 2012)
Schütze, André; Gries, Wolfgang; Kolossa-Gehring, Marike; Apel, Petra; Schröter-Kermani, Christa; Fiddicke, Ulrike; Leng, Gabriele; Brüning, Thomas; Koch, Holger M.
International Journal of Hygiene and Environmental Health (2015), online 1 June 2015, 2015
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Internal exposure of young German adults to di(2-propylheptyl) phthalate (DPHP): Trends in 24-h urine samples from the German Environmental Specimen Bank 1999-2017
Schmidtkunz, Christoph; Gries, Wolfgang; Weber, Till; Leng, Gabriele; Kolossa-Gehring, Marike
International Journal of Hygiene and Environmental Health (2019), online 14 February 2019, 2019